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Beneficial pulmonary effects of a metalloporphyrinic peroxynitrite decomposition catalyst in burn and smoke inhalation injury

During acute lung injury, nitric oxide (NO) exerts cytotoxic effects by reacting with superoxide radicals, yielding the reactive nitrogen species peroxynitrite (ONOO(−)). ONOO(−) exerts cytotoxic effects, among others, by nitrating/nitrosating proteins and lipids, by activating the nuclear repair en...

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Bibliografiske detaljer
Main Authors: Lange, Matthias, Szabo, Csaba, Enkhbaatar, Perenlei, Connelly, Rhykka, Horvath, Eszter, Hamahata, Atsumori, Cox, Robert A., Esechie, Aimalohi, Nakano, Yoshimitsu, Traber, Lillian D., Herndon, David N., Traber, Daniel L.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043813/
https://ncbi.nlm.nih.gov/pubmed/21075825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00277.2010
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