Beneficial pulmonary effects of a metalloporphyrinic peroxynitrite decomposition catalyst in burn and smoke inhalation injury

During acute lung injury, nitric oxide (NO) exerts cytotoxic effects by reacting with superoxide radicals, yielding the reactive nitrogen species peroxynitrite (ONOO(−)). ONOO(−) exerts cytotoxic effects, among others, by nitrating/nitrosating proteins and lipids, by activating the nuclear repair en...

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Detalhes bibliográficos
Main Authors: Lange, Matthias, Szabo, Csaba, Enkhbaatar, Perenlei, Connelly, Rhykka, Horvath, Eszter, Hamahata, Atsumori, Cox, Robert A., Esechie, Aimalohi, Nakano, Yoshimitsu, Traber, Lillian D., Herndon, David N., Traber, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043813/
https://ncbi.nlm.nih.gov/pubmed/21075825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00277.2010
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