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Reactive oxygen species cause endothelial dysfunction in chronic flow overload

Although elevation of shear stress increases production of vascular reactive oxygen species (ROS), the role of ROS in chronic flow overload (CFO) has not been well investigated. We hypothesize that CFO increases ROS production mediated in part by NADPH oxidase, which leads to endothelial dysfunction...

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Bibliografski detalji
Glavni autori: Lu, X., Guo, X., Wassall, C. D., Kemple, M. D., Unthank, J. L., Kassab, G. S.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043782/
https://ncbi.nlm.nih.gov/pubmed/21127212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00786.2009
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