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sis (platelet-derived growth factor B chain) gene transcript levels are elevated in human atherosclerotic lesions compared to normal artery.

Arterial smooth muscle cell (SMC) proliferation is thought to be an essential aspect of the development of human atherosclerotic lesions. In this study we posed the question, could a growth factor gene be transcriptionally active in atherosclerotic tissue? We found that transcripts from the sis gene...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Barrett, T B, Benditt, E P
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2434949/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.4.1099
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