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Rapid and Sensitive Loop-Mediated Isothermal Amplification Test for Clostridium difficile Detection Challenges Cytotoxin B Cell Test and Culture as Gold Standard

Compared to the composite gold standard cytotoxin B assay and toxigenic culture, the loop-mediated isothermal amplification (LAMP) test for Clostridium difficile had a sensitivity and specificity of 98%, positive predictive value of 92%, and negative predictive value of >99%. A one-hour turnaroun...

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Detalhes bibliográficos
Main Authors: Norén, Torbjörn, Alriksson, Ingegärd, Andersson, Josefin, Åkerlund, Thomas, Unemo, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043499/
https://ncbi.nlm.nih.gov/pubmed/21106782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01824-10
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