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Expression of Bmi-1 in Epidermis Enhances Cell Survival by Altering Cell Cycle Regulatory Protein Expression and Inhibiting Apoptosis

The polycomb group (PcG) genes are epigenetic suppressors of gene expression that play an important role in development. In this study, we examine the role of Bmi-1 (B-cell-specific Moloney murine leukemia virus integration site 1) as a regulator of human epidermal keratinocyte survival. We identify...

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Bibliografske podrobnosti
Main Authors: Lee, Kathy, Adhikary, Gautam, Balasubramanian, Sivaprakasam, Gopalakrishnan, Ramamurthy, McCormick, Thomas, Dimri, Goberdhan P., Eckert, Richard L., Rorke, Ellen A.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043461/
https://ncbi.nlm.nih.gov/pubmed/17625597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jid.5700949
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