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Expression of Bmi-1 in Epidermis Enhances Cell Survival by Altering Cell Cycle Regulatory Protein Expression and Inhibiting Apoptosis

The polycomb group (PcG) genes are epigenetic suppressors of gene expression that play an important role in development. In this study, we examine the role of Bmi-1 (B-cell-specific Moloney murine leukemia virus integration site 1) as a regulator of human epidermal keratinocyte survival. We identify...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Kathy, Adhikary, Gautam, Balasubramanian, Sivaprakasam, Gopalakrishnan, Ramamurthy, McCormick, Thomas, Dimri, Goberdhan P., Eckert, Richard L., Rorke, Ellen A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043461/
https://ncbi.nlm.nih.gov/pubmed/17625597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jid.5700949
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