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Specificity and efficiency of editing of mismatches involved in the formation of base-substitution mutations by the 3'----5' exonuclease activity of phage T4 DNA polymerase.

The specificity and efficiency of base-mispair editing by the 3'----5' exonuclease activity of phage T4 DNA polymerase has been measured using a sensitive infectivity assay. A series of oligodeoxynucleotide primer chains was synthesized chemically. These primers, when hybridized to phi X174 single-s...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Sinha, N K
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304330/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029763/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.4.915
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