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Inborn and acquired metabolic defects in cancer

The observation that altered metabolism is the fundamental cause of cancer was made by Otto Warburg nearly a century ago. However, the subsequent identification of oncogenes and tumor suppressor genes has displaced Warburg's theory pointing towards genetic aberrations as the underlining cause o...

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Detalhes bibliográficos
Main Authors: Frezza, Christian, Pollard, Patrick J, Gottlieb, Eyal
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043233/
https://ncbi.nlm.nih.gov/pubmed/21301796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-011-0728-4
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