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Characterization of the Terminal Activation Step Catalyzed by Oxygenase CmmOIV of the Chromomycin Biosynthetic Pathway from Streptomyces griseus

Inactivation and initial interrogation of key oxygenase CmmOIV of the biosynthetic pathway of chromomycin A(3) in Streptomyces griseus ssp. griseus revealed that a completely methylated and acetylated prechromomycin is the preferred substrate of this enzyme. This suggests that the three sugar decora...

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Autors principals: Bosserman, Mary A., Flórez, Ana B., Shaaban, Khaled A., Braña, Alfredo F., Salas, Jose A., Méndez, Carmen, Rohr, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043137/
https://ncbi.nlm.nih.gov/pubmed/21244022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1016205
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