Regeneration of the Exocrine Pancreas Is Delayed in Telomere-Dysfunctional Mice

INTRODUCTION: Telomere shortening is a cell-intrinsic mechanism that limits cell proliferation by induction of DNA damage responses resulting either in apoptosis or cellular senescence. Shortening of telomeres has been shown to occur during human aging and in chronic diseases that accelerate cell tu...

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Main Authors: von Figura, Guido, Wagner, Martin, Nalapareddy, Kodandaramireddy, Hartmann, Daniel, Kleger, Alexander, Guachalla, Luis Miguel, Rolyan, Harshvardhan, Adler, Guido, Rudolph, Karl Lenhard
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043103/
https://ncbi.nlm.nih.gov/pubmed/21364961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017122
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