Plasmin Inhibitors Prevent Leukocyte Accumulation and Remodeling Events in the Postischemic Microvasculature

Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear. Using in vivo microscopy on the cremaster muscle of male C57BL/6 mice, aprotinin as well a...

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Bibliografiske detaljer
Main Authors: Reichel, Christoph A., Lerchenberger, Max, Uhl, Bernd, Rehberg, Markus, Berberich, Nina, Zahler, Stefan, Wymann, Matthias P., Krombach, Fritz
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3043096/
https://ncbi.nlm.nih.gov/pubmed/21364954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017229
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