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Molecular mapping of point mutations in the period gene that stop or speed up biological clocks in Drosophila melanogaster.

The pero1 and the pers mutations in Drosophila melanogaster, which seem to eliminate or speed up, respectively, the clocks underlying biological rhythmicity, were mapped to single nucleotides. Chimeric DNA fragments consisting of well-defined wild-type plus mutant DNA subsegments were constructed, i...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Yu, Q, Jacquier, A C, Citri, Y, Hamblen, M, Hall, J C, Rosbash, M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304300/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3027703/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.3.784
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