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Aplexone targets the HMG-CoA reductase pathway and differentially regulates arteriovenous angiogenesis

Arterial and venous endothelial cells exhibit distinct molecular characteristics at early developmental stages. These lineage-specific molecular programs are instructive to the development of distinct vascular architectures and physiological conditions of arteries and veins, but their roles in angio...

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Hlavní autoři: Choi, Jayoung, Mouillesseaux, Kevin, Wang, Zhiming, Fiji, Hannah D. G., Kinderman, Sape S., Otto, Georg W., Geisler, Robert, Kwon, Ohyun, Chen, Jau-Nian
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042872/
https://ncbi.nlm.nih.gov/pubmed/21307094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.054049
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