Gene targeting by the vitamin D response element binding protein reveals a role for vitamin D in osteoblast mTOR signaling

Transcriptional regulation by hormonal 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] involves occupancy of vitamin D response elements (VDREs) by the VDRE binding protein (VDRE-BP) or 1,25(OH)(2)D(3)-bound vitamin D receptor (VDR). This relationship is disrupted by elevated VDRE-BP, causing a form of...

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Detalhes bibliográficos
Main Authors: Lisse, Thomas S., Liu, Ting, Irmler, Martin, Beckers, Johannes, Chen, Hong, Adams, John S., Hewison, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2011
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042839/
https://ncbi.nlm.nih.gov/pubmed/21123297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-172577
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