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Functional analysis of Rfx6 and mutant variants associated with neonatal diabetes

Mutations in rfx6 were recently associated with Mitchell-Riley syndrome, which involves neonatal diabetes, and other digestive system defects. To better define the function of Rfx6 in early endoderm development we cloned the Xenopus homologue. Expression of rfx6 begins early, showing broad expressio...

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Detalhes bibliográficos
Main Authors: Pearl, Esther J., Jarikji, Zeina, Horb, Marko E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042741/
https://ncbi.nlm.nih.gov/pubmed/21215266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.12.043
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