Myeloid-Specific Deletion of the Mineralocorticoid Receptor Reduces Infarct Volume and Alters Inflammation During Cerebral Ischemia

BACKGROUND AND PURPOSE: Mineralocorticoid receptor (MR) antagonists have protective effects in rodent models of ischemic stroke, but the cell-type-specific actions of these drugs are unknown. In the present study, we examined the contribution of myeloid cell MR during focal cerebral ischemia using m...

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Detalhes bibliográficos
Main Authors: Frieler, Ryan A., Meng, He, Duan, Sheng Zhong, Berger, Stefan, Schütz, Günther, He, Yangdong, Xi, Guohua, Wang, Michael M., Mortensen, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042719/
https://ncbi.nlm.nih.gov/pubmed/21106954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.110.598441
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