Vitamin K-dependent carboxylase: possible role of the substrate "propeptide" as an intracellular recognition site.

The liver microsomal vitamin K-dependent carboxylase catalyzes the posttranslational conversion of specific glutamate residues to gamma-carboxyglutamate residues in a limited number of proteins. A number of these proteins have been shown to contain a homologous basic amino acid-rich "propeptide...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Suttie, J W, Hoskins, J A, Engelke, J, Hopfgartner, A, Ehrlich, H, Bang, N U, Belagaje, R M, Schoner, B, Long, G L
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1987
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304269/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3543932/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.3.634
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