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Clinical significance of K-ras and BRAF mutations in Chinese colorectal cancer patients

AIM: To identify and assess mutations in the K-ras and BRAF genes in a cohort of Chinese patients with colorectal cancer (CRC) for their association with various clinicopathological parameters and prognosis. METHODS: Genomic DNA was isolated from frozen tissues. Pyrosequencing analysis was conducted...

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Detalhes bibliográficos
Main Authors: Shen, Hong, Yuan, Ying, Hu, Han-Guang, Zhong, Xian, Ye, Xiao-Xian, Li, Mo-Dan, Fang, Wei-Jia, Zheng, Shu
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042662/
https://ncbi.nlm.nih.gov/pubmed/21390154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v17.i6.809
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