Preventive but Not Curative Efficacy of Celecoxib on Bladder Carcinogenesis in a Rat Model

To evaluate the effect of a cyclooxygenase 2 inhibitor, celecoxib (CEL), on bladder cancer inhibition in a rat model, when used as preventive versus as curative treatment. The study comprised 52 male Wistar rats, divided in 5 groups, during a 20-week protocol: control: vehicle, carcinogen: 0.05% of...

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Main Authors: Sereno, José, Parada, Belmiro, Reis, Flávio, Cunha, Fernanda X., Teixeira-Lemos, Edite, Garrido, Patrícia, Pinto, Rui, Rocha-Pereira, Petronila, Neto, Paula, Ruivo, José, Rodrigues-Santos, Paulo, Nunes, Sara, Mota, Alfredo, Figueiredo, Arnaldo, Teixeira, Frederico
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042634/
https://ncbi.nlm.nih.gov/pubmed/21403827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/380937
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