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Exploring the Membrane Mechanism of the Bioactive Peptaibol Ampullosporin A Using Lipid Monolayers and Supported Biomimetic Membranes

Ampullosporin A is an antimicrobial, neuroleptic peptaibol, the behavior of which was investigated in different membrane mimetic environments made of egg yolk L-α-phosphatidylcholine. In monolayers, the peptaibol adopted a mixed α/3(10)-helical structure with an in-plane orientation. The binding ste...

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Detalhes bibliográficos
Main Authors: Eid, Marguerita, Rippa, Sonia, Castano, Sabine, Desbat, Bernard, Chopineau, Joël, Rossi, Claire, Béven, Laure
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042626/
https://ncbi.nlm.nih.gov/pubmed/21403824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/179641
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