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Allosteric Response Is both Conserved and Variable across Three CheY Orthologs

A computational method to identify residues likely to initiate allosteric signals has been developed. The method is based on differences within stability and flexibility profiles between wild-type and perturbed structures as computed by a distance constraint model. Application of the approach to thr...

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Détails bibliographiques
Auteurs principaux: Mottonen, James M., Jacobs, Donald J., Livesay, Dennis R.
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042579/
https://ncbi.nlm.nih.gov/pubmed/20923659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.043
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