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Role of autophagy in the host response to microbial infection and potential for therapy

There is compelling evidence demonstrating a key role for autophagy in host defense against microbial infections. Induction and regulation of autophagy involves complex pathways including signaling molecules that have widespread roles in cell biological functions. For example, inhibiting mTOR by rap...

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Detalhes bibliográficos
Main Authors: Fabri, Mario, Realegeno, Susan E., Jo, Eun-Kyeong, Modlin, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042547/
https://ncbi.nlm.nih.gov/pubmed/21071195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2010.10.010
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