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Stress induces Parallel Changes in Corticotropin Releasing Hormone (CRH) Transcription and Nuclear Translocation of Transducer of Regulated CREB Activity 2 (TORC 2) in Hypothalamic CRH Neurons

Recent studies in vitro have shown that the CREB co-activator, Transducer of Regulated CREB activity (TORC), is required for transcriptional activation of the corticotropin releasing hormone (CRH) gene. To determine the physiological importance of TORC 2 regulating CRH transcription during stress, w...

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Detalhes bibliográficos
Main Authors: Liu, Ying, Knobloch, H. Sophie, Grinevich, Valery, Aguilera, Greti
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042526/
https://ncbi.nlm.nih.gov/pubmed/21121974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2826.2010.02101.x
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