Human anti-endoplasmic reticulum autoantibodies appearing in a drug-induced hepatitis are directed against a human liver cytochrome P-450 that hydroxylates the drug.

"Anti-liver/kidney microsome" (anti-LKM) autoantibodies have been found in the serum of patients with cryptogenic chronic hepatitis and with immunoallergic drug-induced hepatitis, such as those induced by halothane or by tienilic acid (called anti-LKM2 in this case). So far the nature of t...

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Detalhes bibliográficos
Main Authors: Beaune, P, Dansette, P M, Mansuy, D, Kiffel, L, Finck, M, Amar, C, Leroux, J P, Homberg, J C
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC304247/
https://ncbi.nlm.nih.gov/pubmed/3540968
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