Persistent directional cell migration requires ion transport proteins as direction sensors and membrane potential differences in order to maintain directedness

BACKGROUND: Ion transport proteins generate small electric fields that can induce directional cell motility; however, little is known about their mechanisms that lead to directedness. We investigated Na, K-ATPase (NaKA) and Na+/H+ exchanger isoforms (NHE1 and 3) in SaOS-2 and Calvarial osteoblasts,...

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Bibliographic Details
Main Authors: Özkucur, Nurdan, Perike, Srikanth, Sharma, Priyanka, Funk, Richard HW
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042415/
https://ncbi.nlm.nih.gov/pubmed/21255452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-12-4
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