Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial

BACKGROUND: High-dose dexamethasone is a mainstay of therapy for multiple myeloma. We studied whether low-dose dexamethasone in combination with lenalidomide is non-inferior to and has lower toxicity than high-dose dexamethasone plus lenalidomide. METHODS: Patients with untreated symptomatic myeloma...

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Detalhes bibliográficos
Main Authors: Rajkumar, SV, Greipp, P R, Jacobus, S, Callander, N S, Fonseca, R, Vesole, DH, Williams, ME, Abonour, R, Siegel, DS, Katz, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042271/
https://ncbi.nlm.nih.gov/pubmed/19853510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(09)70284-0
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