TRANSGENIC EXPRESSION OF 15-LIPOXYGENASE 2 (15-LOX2) IN MOUSE PROSTATE LEADS TO HYPERPLASIA AND CELL SENESCENCE

15-Lipoxygenase 2 (15-LOX2), a lipid-peroxidizing enzyme, is mainly expressed in the luminal compartment of the normal human prostate and often decreased or lost in prostate cancer. Previous studies from our lab implicate 15-LOX2 as a functional tumor suppressor. To better understand the biological...

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Главные авторы: Suraneni, MV, Schneider-Broussard, R, Moore, JR, Davis, T Calhoun, Maldonado, CJ, Li, H, Newman, RA, Kusewitt, D, Hu, J, Yang, P, Tang, DG
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042242/
https://ncbi.nlm.nih.gov/pubmed/20514017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.197
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