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An efficient hierarchical generalized linear mixed model for pathway analysis of genome-wide association studies
Motivation: In genome-wide association studies (GWAS) of complex diseases, genetic variants having real but weak associations often fail to be detected at the stringent genome-wide significance level. Pathway analysis, which tests disease association with combined association signals from a group of...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3042187/ https://ncbi.nlm.nih.gov/pubmed/21266443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq728 |
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