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Assessment of Poly(Methacrylic Acid-co-N-Vinyl Pyrrolidone) as a Carrier for the Oral Delivery of Therapeutic Proteins Using Caco-2 and HT29-MTX Cell Lines

Hydrogels of poly(methacrylic acid-co-N-vinyl pyrrolidone) were synthesized and evaluated for their use as carriers for oral protein delivery. Insulin loading efficiencies were determined to be near 90% for carriers crosslinked with ethylene glycol dimethacrylate with corresponding weight incorporat...

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Bibliografiske detaljer
Main Authors: Carr, Daniel A., Peppas, Nicholas A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042143/
https://ncbi.nlm.nih.gov/pubmed/19213059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.32395
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