A Phase II Study of 2-Methoxyestradiol (2ME2) NanoCrystal(®) Dispersion (NCD) in Patients with Taxane-Refractory, Metastatic Castrate-Resistant Prostate Cancer (CRPC)

PURPOSE: 2ME2 (Panzem(®)) is a non-estrogenic derivative of estradiol with antiproliferative and antiangiogenic activity. Preclinical data support antitumor activity in prostate cancer. This trial evaluated the efficacy of 2ME2 NCD in patients with taxane-refractory, metastatic CRPC. EXPERIMENTAL DE...

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Hlavní autoři: Harrison, Michael R., Hahn, Noah M., Pili, Roberto, Oh, William K., Hammers, Hans, Sweeney, Christopher, Kim, KyungMann, Perlman, Scott, Arnott, Jamie, Sidor, Carolyn, Wilding, George, Liu, Glenn
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042040/
https://ncbi.nlm.nih.gov/pubmed/20499131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-010-9455-x
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