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Controlled and stochastic retention concentrates dynein at microtubule ends to keep endosomes on track

Bidirectional transport of early endosomes (EEs) involves microtubules (MTs) and associated motors. In fungi, the dynein/dynactin motor complex concentrates in a comet-like accumulation at MT plus-ends to receive kinesin-3-delivered EEs for retrograde transport. Here, we analyse the loading of endos...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schuster, Martin, Kilaru, Sreedhar, Ashwin, Peter, Lin, Congping, Severs, Nicholas J, Steinberg, Gero
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041956/
https://ncbi.nlm.nih.gov/pubmed/21278707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.360
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