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Targeting Notch signalling by the conserved miR-8/200 microRNA family in development and cancer cells

Notch signalling is crucial for the correct development and growth of numerous organs and tissues, and when subverted it can cause cancer. Loss of miR-8/200 microRNAs (miRNAs) is commonly observed in advanced tumours and correlates with their invasion and acquisition of stem-like properties. Here, w...

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Bibliographic Details
Main Authors: Vallejo, Diana M, Caparros, Esther, Dominguez, Maria
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041954/
https://ncbi.nlm.nih.gov/pubmed/21224847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.358
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