Phencyclidine (PCP)-Induced Disruption in Cognitive Performance is Gender-Specific and Associated with a Reduction in Brain-Derived Neurotrophic Factor (BDNF) in Specific Regions of the Female Rat Brain

Phencyclidine (PCP), used to mimic certain aspects of schizophrenia, induces sexually dimorphic, cognitive deficits in rats. In this study, the effects of sub-chronic PCP on expression of brain-derived neurotrophic factor (BDNF), a neurotrophic factor implicated in the pathogenesis of schizophrenia,...

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Main Authors: Snigdha, Shikha, Neill, Joanna C., McLean, Samantha L., Shemar, Gaurav K., Cruise, Leonie, Shahid, Mohammed, Henry, Brian
Format: Artigo
Jezik:Inglês
Izdano: Humana Press Inc 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041899/
https://ncbi.nlm.nih.gov/pubmed/20852970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-010-9447-5
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