(5Z,13E)-(15S)-9 alpha,11 beta,15-trihydroxyprosta-5,13-dien-1-oic acid (9 alpha,11 beta-prostaglandin F2): formation and metabolism by human lung and contractile effects on human bronchial smooth muscle.

Prostaglandin D2 (PGD2) was recently found to be stereospecifically converted to the compound (5Z,13E)-(15S)-9 alpha,11 beta,15-trihydroxyprosta-5,13-dien-1-oic acid (9 alpha,11 beta-PGF2) by a human liver cytosolic NADPH-dependent 11-ketoreductase enzyme. Because PGD2 is a potent bronchoconstrictor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Seibert, K, Sheller, J R, Roberts, L J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1987
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC304182/
https://ncbi.nlm.nih.gov/pubmed/3467352
Etiketak: Etiketa erantsi
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