Filaggrin Gene Defects Are Independent Risk Factors for Atopic Asthma in a Polish Population: A Study in ECAP Cohort

BACKGROUND: FLG null variants of which 2282del4 and R501X are the most frequent in Caucasians are established risk factors for atopic dermatitis (AD) with an effect probably mediated through impairment of epidermal barrier. Among subjects with AD FLG defects are also consistently associated with ast...

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Bibliografiska uppgifter
Huvudupphovsmän: Ponińska, Joanna, Samoliński, Bolesław, Tomaszewska, Aneta, Raciborski, Filip, Samel-Kowalik, Piotr, Walkiewicz, Artur, Lipiec, Agnieszka, Piekarska, Barbara, Komorowski, Jarosław, Krzych-Fałta, Edyta, Namysłowski, Andrzej, Borowicz, Jacek, Kostrzewa, Grażyna, Majewski, Sławomir, Płoski, Rafał
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2011
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041817/
https://ncbi.nlm.nih.gov/pubmed/21365004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016933
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