Filaggrin Gene Defects Are Independent Risk Factors for Atopic Asthma in a Polish Population: A Study in ECAP Cohort

BACKGROUND: FLG null variants of which 2282del4 and R501X are the most frequent in Caucasians are established risk factors for atopic dermatitis (AD) with an effect probably mediated through impairment of epidermal barrier. Among subjects with AD FLG defects are also consistently associated with ast...

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Detalhes bibliográficos
Main Authors: Ponińska, Joanna, Samoliński, Bolesław, Tomaszewska, Aneta, Raciborski, Filip, Samel-Kowalik, Piotr, Walkiewicz, Artur, Lipiec, Agnieszka, Piekarska, Barbara, Komorowski, Jarosław, Krzych-Fałta, Edyta, Namysłowski, Andrzej, Borowicz, Jacek, Kostrzewa, Grażyna, Majewski, Sławomir, Płoski, Rafał
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041817/
https://ncbi.nlm.nih.gov/pubmed/21365004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016933
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