T-Cell Immune Responses Against Env from CRF12_BF and Subtype B HIV-1 Show High Clade-Specificity that Can Be Overridden by Multiclade Immunizations

BACKGROUND: The extreme genetic diversity of the human immunodeficiency virus type 1 (HIV-1) poses a daunting challenge to the generation of an effective AIDS vaccine. In Argentina, the epidemic is characterized by the high prevalence of infections caused by subtype B and BF variants. The aim of thi...

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Détails bibliographiques
Auteurs principaux: Mónaco, Daniela C., Rodríguez, Ana M., Pascutti, María F., Carobene, Mauricio, Falivene, Juliana, Gómez, Alejandro, Maeto, Cynthia, Turk, Gabriela, Nájera, José L., Esteban, Mariano, Gherardi, M. Magdalena
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041790/
https://ncbi.nlm.nih.gov/pubmed/21364754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017185
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