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Induction of DNA synthesis in isolated nuclei by cytoplasmic factors: inhibition by protease inhibitors.

Cytoplasmic extracts from spontaneously proliferating and mitogen-activated lymphoid cells contain a protein factor called ADR (activator of DNA replication) that induces DNA synthesis in isolated quiescent nuclei. ADR-containing preparations have proteolytic activity, as indicated by their ability...

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Bibliographic Details
Main Authors: Wong, R L, Gutowski, J K, Katz, M, Goldfarb, R H, Cohen, S
Format: Artigo
Language:Inglês
Published: 1987
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC304179/
https://ncbi.nlm.nih.gov/pubmed/3540956
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