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BCR-ABL1-independent PI3Kinase activation causing imatinib-resistance
BACKGROUND: The BCR-ABL1 translocation occurs in chronic myeloid leukemia (CML) and in 25% of cases with acute lymphoblastic leukemia (ALL). The advent of tyrosine kinase inhibitors (TKI) has fundamentally changed the treatment of CML. However, TKI are not equally effective for treating ALL. Further...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3041785/ https://ncbi.nlm.nih.gov/pubmed/21299849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-4-6 |
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