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The Role of Recombination for the Coevolutionary Dynamics of HIV and the Immune Response

The evolutionary implications of recombination in HIV remain not fully understood. A plausible effect could be an enhancement of immune escape from cytotoxic T lymphocytes (CTLs). In order to test this hypothesis, we constructed a population dynamic model of immune escape in HIV and examined the vir...

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Detalhes bibliográficos
Main Authors: Mostowy, Rafal, Kouyos, Roger D., Fouchet, David, Bonhoeffer, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041767/
https://ncbi.nlm.nih.gov/pubmed/21364750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0016052
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