Galectin-1 is expressed in early-type neural progenitor cells and down-regulates neurogenesis in the adult hippocampus

BACKGROUND: In the adult mammalian brain, neural stem cells (NSCs) proliferate in the dentate gyrus (DG) of the hippocampus and generate new neurons throughout life. A multimodal protein, Galectin-1, is expressed in neural progenitor cells (NPCs) and implicated in the proliferation of the NPCs in th...

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Main Authors: Imaizumi, Yoichi, Sakaguchi, Masanori, Morishita, Tsuyoshi, Ito, Mamoru, Poirier, Françoise, Sawamoto, Kazunobu, Okano, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041742/
https://ncbi.nlm.nih.gov/pubmed/21269521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-4-7
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