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Differences in the epigenetic regulation of MT-3 gene expression between parental and Cd(+2 )or As(+3 )transformed human urothelial cells

BACKGROUND: Studies have shown that metallothionein 3 (MT-3) is not expressed in normal urothelium or in the UROtsa cell line, but is expressed in urothelial cancer and in tumors generated from the UROtsa cells that have been transformed by cadmium (Cd(+2)) or arsenite (As(+3)).The present study had...

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Autors principals: Somji, Seema, Garrett, Scott H, Toni, Conrad, Zhou, Xu Dong, Zheng, Yun, Ajjimaporn, Amornpan, Sens, Mary Ann, Sens, Donald A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041731/
https://ncbi.nlm.nih.gov/pubmed/21303554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-2
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