Evolutionary and genetic implications of sequence variation in two nonallelic HLA-DR beta-chain cDNA sequences.

Most HLA haplotypes carry two expressed DR beta-chain genes; in the DR4 haplotype, the polymorphic locus has been called DR beta 1 and the apparently nonpolymorphic locus has been called DR beta 2. We have isolated nearly full-length DR beta-chain cDNA clones representing each of these two loci from...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Curtsinger, J M, Hilden, J M, Cairns, J S, Bach, F H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304172/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3467350/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.1.209
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