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Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity.

The myc family of oncogenes contains coding sequences that have been preserved in different species for over 400 million years. This conservation (which implies functional selection) is broadly represented throughout the C-terminal portion of the human c-myc protein but is largely restricted to thre...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Sarid, J, Halazonetis, T D, Murphy, W, Leder, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1987
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304164/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3467348/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.1.170
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