Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity.
The myc family of oncogenes contains coding sequences that have been preserved in different species for over 400 million years. This conservation (which implies functional selection) is broadly represented throughout the C-terminal portion of the human c-myc protein but is largely restricted to thre...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1987
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304164/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3467348/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.1.170 |
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