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Aberrant Activation of the Androgen Receptor by NF-κB2/p52 in Prostate Cancer Cells

Prostate cancer initiation and progression are uniquely dependent on the androgen receptor (AR). Even when the cancer progresses to a castration-resistant stage, AR signaling remains active via a variety of mechanisms. In the present study, we showed that NF-κB/p52 can activate the AR, resulting in...

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Detalhes bibliográficos
Main Authors: Nadiminty, Nagalakshmi, Lou, Wei, Sun, Meng, Chen, Jun, Yue, Jiao, Kung, Hsing-Jien, Evans, Christopher P., Zhou, Qinghua, Gao, Allen C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041633/
https://ncbi.nlm.nih.gov/pubmed/20388792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3703
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