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Longitudinal versus Cross-sectional Evaluations of Leukocyte Telomere Length Dynamics: Age-Dependent Telomere Shortening is the Rule

BACKGROUND. Leukocyte telomere length (LTL) is considered a biomarker of human aging and based on cross-sectional studies it shortens with age. However, longitudinal studies reported that many adults display LTL lengthening. METHODS. Using Southern blots, we compared cross-sectional rates of age-rel...

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Detalhes bibliográficos
Main Authors: Chen, W., Kimura, M., Kim, S., Cao, X., Srinivasan, S. R., Berenson, G. S., Kark, J. D., Aviv, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041470/
https://ncbi.nlm.nih.gov/pubmed/21310811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glq223
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