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cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.

We have isolated and sequenced a cDNA encoding the human beta 2-adrenergic receptor. The deduced amino acid sequence (413 residues) is that of a protein containing seven clusters of hydrophobic amino acids suggestive of membrane-spanning domains. While the protein is 87% identical overall with the p...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kobilka, B K, Dixon, R A, Frielle, T, Dohlman, H G, Bolanowski, M A, Sigal, I S, Yang-Feng, T L, Francke, U, Caron, M G, Lefkowitz, R J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC304138/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3025863/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.1.46
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