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Evolutionary Changes of the Target Sites of Two MicroRNAs Encoded in the Hox Gene Cluster of Drosophila and Other Insect Species

MicroRNAs (miRs) are noncoding RNAs that regulate gene expression at the post-transcriptional level. In animals, the target sites of a miR are generally located in the 3′ untranslated regions (UTRs) of messenger RNAs. However, how the target sites change during evolution is largely unknown. MiR-iab-...

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Autors principals: Miura, Sayaka, Nozawa, Masafumi, Nei, Masatoshi
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041157/
https://ncbi.nlm.nih.gov/pubmed/21187351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evq088
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