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Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway

Host Cell Factor 1 (HCF-1) plays critical roles in regulating gene expression in a plethora of physiological processes. HCF-1 is first synthesized as a precursor, and subsequently specifically proteolytically cleaved within a large middle region termed the proteolytic processing domain (PPD). Althou...

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Autors principals: Daou, Salima, Mashtalir, Nazar, Hammond-Martel, Ian, Pak, Helen, Yu, Helen, Sui, Guangchao, Vogel, Jodi L., Kristie, Thomas M., Affar, El Bachir
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041071/
https://ncbi.nlm.nih.gov/pubmed/21285374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013822108
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