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Widespread establishment and regulatory impact of Alu exons in human genes

The Alu element has been a major source of new exons during primate evolution. Thousands of human genes contain spliced exons derived from Alu elements. However, identifying Alu exons that have acquired genuine biological functions remains a major challenge. We investigated the creation and establis...

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Detalhes bibliográficos
Main Authors: Shen, Shihao, Lin, Lan, Cai, James J., Jiang, Peng, Kenkel, Elizabeth J., Stroik, Mallory R., Sato, Seiko, Davidson, Beverly L., Xing, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041063/
https://ncbi.nlm.nih.gov/pubmed/21282640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012834108
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