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Microbial Production and Biomedical Applications of Lovastatin

Lovastatin is a potent hypercholesterolemic drug used for lowering blood cholesterol. Lovastatin acts by competitively inhibiting the enzyme, 3-hydroxy-3-methylglutaryl coenzyme A reductase involved in the biosynthesis of cholesterol. Commercially lovastatin is produced by a variety of filamentous f...

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Bibliographic Details
Main Authors: Seenivasan, A., Subhagar, S., Aravindan, R., Viruthagiri, T.
Format: Artigo
Language:Inglês
Published: Medknow Publications 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040861/
https://ncbi.nlm.nih.gov/pubmed/21369428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0250-474X.49087
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