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Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesis
Colon cancer, the second leading cause of cancer-related mortality worldwide, originates from the malignant transformation of intestinal epithelial cells. The intestinal epithelium undergoes a highly organized process of rapid regeneration along the crypt-villus axis, characterized by proliferation,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3040833/ https://ncbi.nlm.nih.gov/pubmed/20592492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.3.12539 |
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